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INTERNSHIP DETAILS

R&D Novel CAR Intern

CompanyLegend Biotech US

LocationPhiladelphia

Work ModeOn Site

PostedJanuary 13, 2026

Internship Information

Core Responsibilities

The intern will assist in evaluating novel CAR constructs and perform various molecular and cellular biology experiments. They will analyze data and collaborate with cross-functional teams to advance early-stage therapeutic concepts.

Internship Type

full time

Company Size

2309

Visa Sponsorship

Language

English

Working Hours

40 hours

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About The Company

Legend Biotech is a global, commercial-stage biotechnology company developing and manufacturing novel therapies. We explore and apply innovative technologies to deliver cutting-edge options for patients around the world. Our corporate headquarters is located in Somerset, NJ, and our manufacturing footprint includes facilities in the United States, China and the Belgium.

About the Role

<div class="content-intro">Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.   Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.  </div>Legend Biotech is seeking a R&D Novel CAR Intern as part of the Research & Early Development team based in Philadelphia, PA. Role Overview This position offers hands‑on experience in designing and developing novel CAR constructs or vectors for next‑generation cell therapies. The intern will perform molecular/cellular biology experiments, analyze data, and collaborate across teams to advance early‑stage therapeutic concepts. Key Responsibilities <ul> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Assist in evaluating novel CAR constructs/vectors using molecular and cellular techniques.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Perform cell culture, transfection, and functional assays to assess CAR/vector performance.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Analyze experimental data, maintain accurate records, and present findings to the research team.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Collaborate cross‑functionally to progress early discovery programs.</li> </ul> <div class="col-xs-12 no-horiz-padding">Requirements</div> <ul> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Basic knowledge of molecular biology, cell culture, and immunology principles.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Familiarity with flow cytometry, PCR, ELISA, or other immunoassays a plus.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Strong attention to detail, organizational skills, and ability to work in a fast‑paced environment.</li> </ul> Skills You’ll Gain <ul> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Exposure to cutting‑edge CAR‑T research.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Technical skills in functional testing (flow cytometry, PCR, ELISA) and scientific communication.</li> <li style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Mentorship and opportunities to contribute to impactful projects.</li> </ul> #Li-JR1 #Li-Contract<div class="content-conclusion">Benefits We are committed to creating a workplace where employees can thrive - both professionally and personally. To attract and retain top talent in a highly competitive industry, we offer a best-in-class benefits package that supports well-being, financial stability, and long-term career growth. Our offerings are designed to meet the diverse needs of our team members and their families, ensuring they feel valued and supported every step of the way. Highlights include medical, dental, and vision insurance as well as a 401(k)-retirement plan with company match that vest fully on day one. Equity and stock options are available to employees in eligible roles. We offer eight weeks of paid parental leave after just three months of employment, and a paid time off policy that includes vacation days, personal days, sick time, 11 company holidays, and 3 floating holidays. Additional benefits include flexible spending and health savings accounts, life and AD&D insurance, short- and long-term disability coverage, legal assistance, and supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance. We also provide commuter benefits, family planning and care resources, well-being initiatives, and peer-to-peer recognition programs - demonstrating our ongoing commitment to building a culture where our people feel empowered, supported, and inspired to do their best work. Please note: These benefits are offered exclusively to permanent employees. Contract employees are not eligible for benefits through Legend Biotech.   EEO Statement It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.   Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company. Legend may adjust base salary or other discretionary compensation at any time based on individual, team, performance, or market conditions.   Legend Biotech maintains a drug-free workplace.</div>

Key Skills

Molecular BiologyCell CultureImmunologyFlow CytometryPCRELISAAttention to DetailOrganizational SkillsData AnalysisCollaborationFunctional AssaysTransfectionRecord KeepingScientific CommunicationCellular TechniquesTherapeutic Concepts