INTERNSHIP DETAILS
Protein Sciences and Lead Discovery Co-Op
CompanyKymera Therapeutics
LocationWatertown
Work ModeOn Site
PostedJanuary 27, 2026

Internship Information
Core Responsibilities
The co-op student will assist cross-functional teams with compound screening and the development and validation of biochemical and biophysical assays to characterize protein interactions. This includes assisting in the discovery of chemical starting points using various screening technologies and validating hits using a suite of biophysical technologies.
Internship Type
full time
Salary Range
$22 - $28
Company Size
273
Visa Sponsorship
No
Language
English
Working Hours
40 hours
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About The Company
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on delivering oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years.
About the Role
<h3><strong>Who we are:</strong></h3>
<p>Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit <a href="https://www.kymeratx.com" target="_blank">www.kymeratx.com</a> or follow us on <a href="https://twitter.com/KymeraTx?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor" target="_blank">X (formerly Twitter)</a> or <a href="http://www.linkedin.com/company/kymeratherapeutics" target="_blank">LinkedIn</a>. </p>
<p> </p>
<h3><strong>How we work:</strong></h3>
<ul>
<li><strong>PIONEER</strong>: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.</li>
<li><strong>COLLABORATE</strong>: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.</li>
<li><strong>BELONG</strong>: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.</li>
</ul>
<p> </p>
<h3><strong>How you’ll make an impact:</strong></h3>
<p>We are seeking a talented and enthusiastic co-op student to join the Protein Sciences and Lead Discovery (PSLD) team at Kymera. This person will gain industry-relevant experience through assisting cross-functional teams with compound screening and biochemical/biophysical assay development on early-stage projects. The ideal candidate is a highly-motivated self-starter, an agile learner, collaborative, and looking to transform patient’s lives through the development of novel therapeutics.</p>
<ul>
<li>Development and validation of fluorescence-based biochemical and biophysical assays to characterize protein-compound and/or protein-protein interactions.</li>
<li>Assist in the discovery of chemical starting points for early-stage projects using screening technologies, including but not limited to DNA-encoded libraries, automated high-throughput fluorescence or activity-based assays, and fragment-based methods.</li>
<li>Assist in the validation of screening hits using a suite of technologies including surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), thermal shift assays, dynamic light scattering, time-resolved FRET or fluorescence polarization-based assays, and NMR.</li>
<li>Work with contract research organizations to oversee generation of protein reagents to facilitate biochemical/biophysical experiments.</li>
</ul>
<p> </p>
<h3><strong>Skills and experience you’ll bring:</strong></h3>
<ul>
<li>Currently pursuing a BS or MS degree in chemistry, biology, biochemistry, biophysics, biotechnology, or a related field.</li>
<li>Hands-on laboratory experience in protein science, biochemistry, biophysics, or related fields. Prior exposure to fluorescence-based techniques, running assays in 384/1536-well format, and protein sciences a plus.</li>
<li>Ability to work well independently in a collaborative team environment. Comfortable in presenting results to small groups and cross-function teams.</li>
<li>Ability to be onsite in Watertown, Ma July - December 2026 (start/end dates are flexible)</li>
</ul>
<p> </p>
<div><em>Equal Employment Opportunity</em></div>
<p><span class="ui-provider a b c d e f g h i j k l m n o p q r s t u v w x y z ab ac ae af ag ah ai aj ak">Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.</span></p>
<p> </p>
<p><em><span class="ui-provider a b c d e f g h i j k l m n o p q r s t u v w x y z ab ac ae af ag ah ai aj ak">Compensation</span></em></p>
<ul>
<li>The anticipated pay rate range for this role is $22 – $28/hour.</li>
<li>Actual rate is based on academic level.</li>
</ul>
<p> </p>
<p> </p>
Key Skills
Protein SciencesLead DiscoveryCompound ScreeningAssay DevelopmentBiochemical AssaysBiophysical AssaysFluorescence-based TechniquesDNA-encoded LibrariesHigh-throughput AssaysFragment-based MethodsSurface Plasmon ResonanceIsothermal Titration CalorimetryThermal Shift AssaysDynamic Light ScatteringTime-resolved FRETFluorescence Polarization
Categories
Science & ResearchHealthcareEngineering
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Protein SciencesLead DiscoveryCompound ScreeningAssay DevelopmentBiochemical Assays
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Week 1:Technical Foundations2
Week 2:Protein Sciences3
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