INTERNSHIP DETAILS
Summer Research Intern - Molecular and Cellular Biology (Undergraduate level)
CompanySepterna
LocationSouth San Francisco
Work ModeOn Site
PostedJanuary 28, 2026

Internship Information
Core Responsibilities
The intern will contribute to cell-based assay development and be assigned to a specific project for the 3-month internship term. They will participate in weekly project team meetings and provide a final presentation of their project work to senior leaders.
Internship Type
full time
Company Size
127
Visa Sponsorship
No
Language
English
Working Hours
40 hours
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About The Company
Septerna is on a mission to make the promise of future GPCR medicines a reality for patients. Combining the latest advances in biochemical, structural and computational drug discovery approaches, we have built an industrialized platform to precisely control and modulate GPCR biology and pharmacology to discover and develop new high-impact medicines. With our Native Complex Platform™, we are opening a new frontier in GPCR small molecule discovery technologies to expand the druggable GPCR landscape.
We are always looking for talented scientists, drug hunters, and business professionals to join our mission to launch a new era of GPCR medicines. If you’re passionate about innovation, energized by teamwork, and fueled by the desire to change patient lives, join us and become a part of the Septerna story!
About the Role
<div class="content-intro"><p> </p>
<p>Septerna is a biotechnology company based in South San Francisco, CA on a mission to develop life-changing medicines for patients with the vision to become the industry-leading G protein-coupled receptor (GPCR)-focused drug discovery company. The company’s Native Complex Platform™ recapitulates GPCRs with their native structure, function, and dynamics outside of the cellular context. This approach enables novel access to modern structural and screening technologies used in industrial-scale drug discovery for the entire class of GPCRs. Septerna has an emerging pipeline of GPCR-targeted small molecule programs with potential for growth to target many GPCRs that have been undruggable and unexploited to date.</p>
<p>We are excited to expand our multidisciplinary team of individuals focused on creating revolutionary medicines to address the unmet needs of patients. At Septerna we strive to embrace diversity of thought, expertise, and background through collaboration. To join our ambitious team, be prepared to bring your real self to work every day; grow and learn from a talented team of drug hunters, scientists, and business professionals; and contribute your passion, creativity, and energy to accomplish our mission. We share a fearless pursuit of ground-breaking innovations and cultivate an environment where our employees succeed by learning from each other and working as a team.</p>
<p>We are committed to the development of meaningful therapeutics for patients with indications of high unmet need. This is a tremendous opportunity to work with talented individuals on the frontlines of therapeutic discovery and development. You will directly help move therapies through preclinical research, positioning them for success in the clinic. The successful candidate will add their passion, unique talents, and expertise to a dynamic team motivated to discover new disease-modifying therapeutics for patients in a fast-paced environment.</p>
<p>For more information see: <a href="http://www.septerna.com">www.septerna.com</a>.</p></div><p><strong>About The Role</strong></p>
<p>The Research Intern program provides each student with real-life hands-on experience, coaching and mentoring, networking opportunities, as well as the opportunity to meet people from various schools throughout the country. We plan to hire a student intern to contribute to cell-based assay development in the Molecular and Cellular Biology research team. The Intern will be assigned to a specific project for the 3-month Internship term.</p>
<p><strong>Opportunity </strong></p>
<ul>
<li>Ownership of a challenging project.</li>
<li>Contribute directly to Septerna’s internal cell-based assay development.</li>
<li>Work alongside exceptional scientists in the field of GPCR drug discovery.</li>
<li>Participate in weekly project team meetings.</li>
<li>Build a network of drug hunters.</li>
<li>Provide a final presentation of project work to senior leaders.</li>
</ul>
<p><strong>Qualifications</strong></p>
<ul>
<li>Pursuing a Bachelors (enrolled student) in molecular biology, cellular biology, chemical biology, biochemistry or related field.</li>
<li>Ability to interpret and analyze experimental data, troubleshoot experiments, and propose solutions to research challenges.</li>
<li>Excellent communication, collaboration, and interpersonal skills</li>
<li>Self-motivated, with the ability to work both independently and collaboratively</li>
<li>Ability to read and digest scientific literature</li>
<li>Strong organizational, problem solving, analytical and quantitative skills</li>
<li>Ability to efficiently manage short timelines</li>
<li>Authorized to work in the U.S. i.e. (applicants who require employer sponsored visas now or in the future are not eligible to apply)</li>
<li>Must be at least 18 years old</li>
<li>Ability to complete 12 consecutive weeks between May and September on-site in South San Francisco.</li>
<li>Enrolled currently in graduate degree at an accredited college/university and returning to the University/and or College following the internship</li>
<li>Strict adherence to lab safety rules and regulations</li>
</ul>
<p><strong>**This opportunity does not provide relocation; individuals being considered must be able to meet the onsite requirements of this role**</strong></p>
<p><strong>Preferred Qualifications</strong></p>
<ul>
<li>Excellent communication, collaboration, and interpersonal skills.</li>
<li>Ability to read and interpret scientific literature.</li>
<li>Strong organizational, project management, problem-solving, analytical, and quantitative skills.</li>
<li>Ability to efficiently manage projects under short timelines.</li>
<li>Experience maintaining accurate experimental records using electronic lab notebooks.</li>
<li>Practical laboratory experience is highly desired and may include, but is not limited to:
<ul>
<li>Molecular biology techniques (e.g., RNA isolation, qRT-PCR)</li>
<li>Cell-based assays and advanced tissue culture techniques</li>
<li>Data analysis using GraphPad Prism, Benchling, Excel, and presentation tools such as PowerPoint</li>
</ul>
</li>
<li><strong>Relocation benefits are not available for this job posting.</strong></li>
</ul>
<p><strong><br></strong>The expected salary range for this position based on the primary location of South San Francisco, CA is $25.00 per hour depending of undergraduate/graduate level and year. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.</p>
<p><br><br><br></p><div class="content-conclusion"><div style="line-height: 1;"> </div>
<div style="line-height: 1;"><span style="font-size: 8pt;"><em>Note to Employment Agencies: Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited. </em></span><span style="font-size: 8pt;"><em>We are an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. </em></span><span style="font-size: 8pt;"><em>Septerna participates in the E-Verify program. </em></span><em><span style="font-size: 8pt;">California Consumer Privacy Act Privacy Notice For Job Applicants. If you are a California resident, click <a href="https://septerna.com/california-consumer-privacy-act-privacy-notice-for-job-applicants/" target="_blank">here</a> for our CCPA Notice.</span></em></div>
<p> </p></div>
Key Skills
Molecular BiologyCellular BiologyChemical BiologyBiochemistryData AnalysisExperimental DesignProblem SolvingCommunicationCollaborationInterpersonal SkillsOrganizational SkillsQuantitative SkillsLaboratory SafetyAssay DevelopmentTissue CultureProject Management
Categories
Science & ResearchHealthcareTechnology
Benefits
Paid Holiday Time Off
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