INTERNSHIP DETAILS

Summer Intern, Protein

CompanyVaxcyte
LocationSan Carlos
Work ModeOn Site
PostedFebruary 25, 2026
Internship Information
Core Responsibilities
The intern will support the design and execution of development studies using the Ambr 15 microbioreactor system to establish operating conditions for cell-free protein synthesis reactions. Responsibilities include performing literature reviews, analyzing experimental data, documenting findings in an SOP, and presenting results to the Protein team.
Internship Type
full time
Salary Range
$23 - $26
Company Size
511
Visa Sponsorship
No
Language
English
Working Hours
32 hours
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About The Company
Vaxcyte is a vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. VAX-31, a 31-valent pneumococcal conjugate vaccine (PCV) candidate being evaluated in a Phase 3 adult clinical program and in a Phase 2 infant clinical program, is being developed for the prevention of invasive pneumococcal disease (IPD) and is the broadest-spectrum PCV candidate in the clinic today. VAX-24, a 24-valent PCV candidate, is designed to cover more serotypes than any infant PCV on-market. VAX-31 and VAX-24 are designed to improve upon standard-of-care PCVs by covering the serotypes in circulation that cause a significant portion of IPD and are associated with high case-fatality rates, antibiotic resistance and meningitis, while maintaining coverage of previously circulating strains. VAX-XL, in earlier-stage development, also leverages the Company’s carrier-sparing, site-specific conjugation technology with the aim of further expanding coverage to deliver the broadest-spectrum candidate in the Company’s PCV franchise. Vaxcyte is re-engineering the way highly complex vaccines are made through XpressCF®, its cell-free protein synthesis platform exclusively licensed from Sutro Biopharma, Inc. Unlike conventional cell-based approaches, the Company’s system for producing difficult-to-make proteins and antigens is intended to accelerate its ability to develop high-fidelity vaccines with enhanced immunological benefits. Vaxcyte’s pipeline also includes VAX-A1, a prophylactic vaccine candidate designed to prevent Group A Strep infections, and VAX-GI, a vaccine candidate designed to prevent Shigella. For more information, visit www.vaxcyte.com.
About the Role

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. 
 
WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:
 
*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.
 
*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.
 
*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.
 
*MODEL EXCELLENCE:  The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

Vaxcyte’s Summer Internship program offers students an opportunity to gain valuable work experience that complements their college curriculum with relevant hands-on work that can shape their future career pathing and interests. 

As a Protein Intern for Vaxcyte, you will work on a project as outlined below:

  • Perform a literature review to understand cell-free protein synthesis (CFPS) and key principles of small-scale bioreactor operation.
  • Support the design and execution of development studies aimed at establishing operating conditions in the Ambr 15 microbioreactor system for maintaining CFPS reaction setpoints (e.g., temperature, dissolved oxygen, and pH).
  • Analyze experimental data to help design next studies or finalize operating conditions for 10 mL CFPS reactions.
  • Document findings by drafting a work practice/SOP for running CFPS reactions in the Ambr 15 system.
  • Present results and recommendations to the Protein team to support ongoing process development efforts.

The Intern will learn and practice:

  • Bioreactor operations and scale-down principles.
  • Data analysis (process trends and analytical results).
  • Electronic lab notebook (ELN) record keeping.
  • Science communication.
  • SOP/work practice writing skills. 

Program Details:

The Internship will begin in June and will be around 10 weeks (8 hours per day) in duration at our San Carlos, California location.

Requirements: 

  • Must be pursuing a Bachelor’s Degree (enrolled student with at least 1 year at university completed) with a focus on Biochemical Engineering, Chemical Engineering, Bioengineering, or Biochemistry.
  • Proficiency in Microsoft Office.
  • Strong attention to detail and work quality.
  • Demonstrates collaboration and teamwork.
  • Enthusiastic-Shows curiosity and is eager to learn.
Reports to: Scientist I, Protein
 
Location: San Carlos, CA
 
Salary Range: The expected salary range for this position is $23-$26 per hour for undergraduate students. Actual pay will be determined based on year of university/college completed. The Summer Internship position will not be eligible for benefits. Relocation and housing stipend will not be offered.

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

 

Key Skills
Literature ReviewCell-Free Protein SynthesisBioreactor OperationData AnalysisSOP WritingMicrosoft OfficeAttention To DetailCollaborationTeamworkCuriosity
Categories
Science & ResearchEngineeringHealthcare