INTERNSHIP DETAILS

Structural Biology Intern

CompanyGenesis Molecular AI
LocationSan Diego
Work ModeOn Site
PostedMarch 13, 2026
Internship Information
Core Responsibilities
The intern will gain structural biology lab skills, specifically in x-ray crystallography and cryoEM, and apply these techniques to an ongoing project. Responsibilities also include documenting all findings and presenting results to mentors at project meetings.
Internship Type
intern
Company Size
158
Visa Sponsorship
No
Language
English
Working Hours
40 hours
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About The Company
Genesis Molecular AI – headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego and offices in New York – is pioneering foundation models for molecular AI to unlock a new era of drug design and development. We are using a proprietary state-of-the-art generative and predictive AI platform called GEMS (Genesis Exploration of Molecular Space), to accelerate and optimize small molecule drug discovery. The GEMS platform integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. GEMS accelerates hit ID through lead optimization and candidate selection by generating promising molecules for synthesis and experimental testing, and iterating this process through cycles of AI-enabled discovery and optimization. We have leveraged GEMS to build an internal pipeline with multiple programs against high-value targets, including data-poor and canonically undruggable targets where GEMS is uniquely advantaged. In addition, Genesis has signed AI platform collaborations across a range of therapeutic areas including Gilead (2024), and Incyte (2025). Genesis has raised over $300M in funding from top AI, technology and biotech investors, including Andreessen Horowitz, Rock Springs Capital, T. Rowe Price, Fidelity, Radical Ventures, NVentures (NVIDIA's VC arm), BlackRock, and Menlo Ventures. To learn more about Genesis Molecular AI, or current employment opportunities, please visit our website.
About the Role

Genesis Molecular AI is pioneering artificial intelligence guided rational drug design to address severe unmet medical needs for patients. Our lab in San Diego seeking a motivated undergraduate or postgraduate student for an immersive internship within our Structural Biology team. This role offers hands-on experience in the end-to-end structure determination process while interacting with cross-functional teams to drive drug discovery efforts. The internship will provide the intern with valuable experience in scientific discovery in an industry setting.

What You Will Do

  • Gain structural biology lab skills (x-ray crystallography and cryoEM) and apply them to a project

  • Document all findings in the structural biology lab

  • Attend project meetings with their mentors and present findings

  • Prepare a report with final findings at the end of the summer

  • Additional duties and responsibilities as required

What you will Bring

  • Currently enrolled in or recently graduated from a program (BS/MS/PhD) in Structural Biology, Biophysics, Biochemistry, Biology, Chemistry, or a related field.

  • Basic laboratory proficiency and a strong desire to learn structural biology techniques.

  • Good multi-tasking, organizational, record keeping, and communication skills, and the ability to work effectively in an interdisciplinary, team-oriented, collaborative, high performance environment

  • Enthusiasm, integrity, self-motivation, strong interpersonal skills, and attention to detail are necessary

About Genesis Molecular AI

Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. The company’s generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets.

Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.

Key Skills
X-ray CrystallographyCryoEMStructural BiologyDrug DesignRecord KeepingCommunicationMulti-taskingOrganizational SkillsScientific Discovery
Categories
Science & ResearchEngineeringHealthcare