RiSE Internship - Targeting CNS Meninges

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The Position

The RiSE program (Roche Internships for Scientific Exchange) is a highly
competitive student research program at Roche. It offers the most talented graduate and medical degree students the opportunity to be fully integrated into our interdisciplinary and international industry R&D environment. As a RiSE student you will enhance your competencies, gain valuable work experience with us, and eventually become part of a world-wide network of RiSE Alumni.

The Neuroscience and Rare Diseases Discovery and Translational Area (NRD DTA) is developing medicines for a range of serious neurological diseases, including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, autism, spinal muscular atrophy, and Huntington’s disease.

As a RiSE student in the NRD DTA you will join the Neurovascular Distribution Lab and work on a joint project between the Neuroimmunology and Neurotechnologies sections at the Roche Innovation Center Basel, Switzerland. We are a
multidisciplinary team with expertise in neuroimmunology, neurovascular biology, blood-brain barrier function, disease biology and in vivo models of the central nervous system.

The Opportunity

• Performing exploratory lab work to investigate the targeting of the CNS meninges using various modalities in vivo

• Visualizing the cranio-meningeal compartment and exploring suitable delivery methods

• Performing animal work (LTK1 or similar required)

• Optimizing dissection and staining conditions for dura and leptomeninges

• Applying state of the art imaging techniques including confocal microscopy

• Using state-of-the-art tissue clearing and lightsheet microscopy to analyze the intact cranio-meningeal compartment

• Summarizing your work for internal and external meetings and draft a publication

• You will be hosted and mentored by a Roche scientist who will guide you through your research and provide you with the needed work infrastructure and collaborative network

Who You Are

• You graduated with a Master's degree less than a year ago OR you are enrolled in a PhD or medical degree program at a university.

• You are looking to expand your experience with an industry internship.

• You hold a valid LTK1/FELASA B animal licence.

• You are proficient in neuroscience and/or vascular biology.

• You have extensive experience in imaging methodologies including whole mount immunofluorescence stainings and you have good knowledge of analysis methods for imaging datasets.

• Experience with dural/leptomeningeal biology and anatomy will be beneficial.

• You are passionate about answering fundamental questions in neurovascular biology with high translational impact.

Additional Information

The preferred start date of the internship is July 2026 or upon availability. Please clearly indicate your preferred starting date on your cover letter.

Application Process

Applications need to include a CV and a cover letter, as well as a letter from your current or former academic supervisor supporting your application to the RiSE Program. 

Please note that due to regulations non-EU/EFTA citizens have to be enrolled at a university and provide a certificate from the university stating that an industry internship is mandatory as part of the university training.

Curious, motivated, and ready to learn? Apply now for our RiSE Internship.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.