Graduate Internship/RiSE - Uncovering novel regulators of Alzheimer's Disease targets (12 months)

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections,  where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

The RiSE program (Roche Internships for Scientific Exchange) is a highly competitive student research program at Roche. It offers the most talented graduate and medical degree students the opportunity to be fully integrated into our interdisciplinary and international industry R&D environment. As a RiSE student you will enhance your competencies, gain valuable work experience with us, and eventually become part of a world-wide network of RiSE Alumni.

The Neuroscience and Rare Diseases Discovery and Translational Area (NRD DTA) is developing medicines for a range of serious neurological diseases, including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, autism, spinal muscular atrophy, and Huntington’s disease.

As RiSE student in the NRD DTA you will join the Brain Delivery group at the Roche Innovation Center Basel, Switzerland, to perform omics data analysis and experimental in vitro work to map the regulatory landscape of Alzheimer’s Disease targets. You will be hosted and mentored by a Roche scientist who will guide you through your research and provide you with the needed work infrastructure and collaborative network.

The Opportunity

• Collaborate closely with computational scientists to analyze sequencing datasets to drive biological insights.

• Design rigorous in vitro experiments informed by your expertise in transcriptomic data interpretation.

• Apply a comprehensive set of molecular cell biology methods in stem-cell derived models to test specific biological hypothesis

• Present and discuss your work in internal meetings.

• Synthesize experimental data for the preparation and submission of high-impact manuscripts for peer-reviewed publication.

Who You Are

• You graduated from a Master's program within the last year

• Or you are enrolled in a PhD or medical degree program at a university

• You are looking to expand your experience with an industry internship

• Extensive experience in the generation and analysis of scRNAseq data

• Hands-on experience with engineering iPSC-based models of brain cell types for functional genomic approaches (e.g. CRISPR)

• A broad skill set with cell and molecular biology assays

Additional Information

The preferred start date of the internship is 11/2026 or upon availability.

Application Process

Applications need to include a CV and a cover letter, as well as a letter from your current or former academic supervisor supporting your application to the RiSE Program. Reference letters are also welcome.

Please note that due to regulations non-EU/EFTA citizens have to be enrolled in a PhD or medical degree program at a university and provide a certificate from the university stating that an industry internship is mandatory as part of the university training.

Curious, motivated, and ready to learn? Apply now for our RiSE Internship.

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.