INTERNSHIP DETAILS

Graduate Research Appointment - Wangensteen Lab

CompanyMayo Clinic
LocationRochester
Work ModeOn Site
PostedJuly 6, 2026
Internship Information
Core Responsibilities
The role involves developing a new drug to treat liver cancer using genetic approaches to target specific vulnerabilities. Responsibilities include integrating RNA interference, CRISPR-based gene therapy, and lipid nanoparticle generation to test molecular medicines for hepatocellular carcinoma.
Internship Type
full time
Company Size
48842
Visa Sponsorship
No
Language
English
Working Hours
40 hours
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About The Company
Mayo Clinic has expanded and changed in many ways, but our values remain true to the vision of our founders. Our primary value – The needs of the patient come first – guides our plans and decisions as we create the future of health care. Join us and you'll find a culture of teamwork, professionalism and mutual respect, and most importantly, a life-changing career. Mayo Clinic was founded in Rochester, Minnesota by brothers Dr. William James Mayo and Dr. Charles Horace Mayo. More than 100 years later, their vision continues to evolve around a single guiding value: "The needs of the patient come first." Today we are the largest integrated, not for-profit medical group practice in the world. We are recognized for high-quality patient care more than any other academic medical center in the nation. These endorsements are very gratifying, but also humbling. They remind us of the tradition that has been entrusted to each one of us, and the legacy of excellence that we uphold every day.
About the Role

The Graduate Research Appointment (GRA) is a post-baccalaureate appointment for participants with an interest in biomedical research. The primary purpose is to provide a post-baccalaureate laboratory research experience that applies skills in science, technology, engineering, or math to biomedical research including basic science or translational research.  GRA participants will have the opportunity to participate in selected graduate classes and seminars while working in this role.

The Genetics of Liver Disease Laboratory develops genetic technologies to identify the molecular drivers of liver disease and cancer and aims to translate those discoveries into new therapeutic strategies. 

The GRA project will focus on the development of a new drug to treat liver cancer, with an emphasis on genetic approaches that can directly target a vulnerability in cancer that we discovered. The work will integrate RNA interference, CRISPR-based gene therapy, lipid nanoparticle generation, and in vivo gene delivery to design, optimize, and test next-generation molecular medicines for hepatocellular carcinoma.


Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.

Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Key Skills
RNA InterferenceCRISPR-based Gene TherapyLipid Nanoparticle GenerationIn Vivo Gene DeliveryBioinformaticsMolecular BiologyCell CultureMouse Handling
Categories
Science & ResearchHealthcareEngineering
Benefits
Medical InsuranceDental InsuranceVision InsuranceHSAFSARetirement Package