INTERNSHIP DETAILS

Intern, Manufacturing Associate, Downstream and Central Services, 6:00 AM - 4:30 PM

CompanyUltragenyx Pharmaceutical
LocationBedford
Work ModeOn Site
PostedNovember 11, 2026
Internship Information
Core Responsibilities
The Manufacturing Associate will support gene therapy manufacturing processes, including downstream and central services operations. Responsibilities include generating and reviewing SOPs, batch records, and supporting quality investigations and facility maintenance.
Internship Type
full time
Salary Range
$23 - $28
Company Size
1576
Visa Sponsorship
No
Language
English
Working Hours
40 hours
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About The Company
Leading with purpose. Every day. “Ultragenyx was founded to advance innovative medicines for rare and ultrarare diseases that have never been treated before. We are delivering transformative therapies across multiple indications, and we have one of the most robust and diverse clinical pipelines in rare disease. Our focus is on doing the right things for patients both during development and commercialization to deliver on the promise of these therapies in a way that's meaningful for rare disease communities.” Emil D. Kakkis, M.D., Ph.D. Chief Executive Officer and President We have an inclusive culture of value and respect. Ultragenyx brings novel products to those living with rare and ultrarare diseases with a focus on debilitating genetic diseases. Founded in 2010, we have rapidly built a diverse portfolio of approved therapies and products aimed at diseases with a high unmet medical need for which many have no approved therapies. It takes courage, care, talent, and dedication to make a meaningful impact for those living with rare diseases, their families and the rare disease community. We put our people first, so they can take care of the rare disease community. We purposefully cultivate and nurture a dynamic, supportive work environment where we encourage every team member to share their new ideas and help us unlock more possibilities. Our team is made up of exceptional and diverse people with a strong passion and commitment to helping those living with rare diseases. By embracing generosity, curiosity, inclusion, and humility we are constantly learning together—fostering an environment that supports profound growth and fulfillment. If you want to have a meaningful impact, do the best work of your career while having fun and growing professionally and personally, come join our team! Visit our community guidelines at: https://ultragenyx.co/community
About the Role
Why Join Us?
 
Be a hero for our rare disease patients
 
At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them. 
 
Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.
 
If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultrafocused – Work together to fearlessly uncover new possibilities

Ultragenyx has multiple Gene Therapy programs in development in the rare and ultrarare disease space, a robust pipeline. Our Manufacturing Associates will support Ultragenyx’s state-of-the-art GMP manufacturing gene therapy manufacturing facility located in Bedford, MA. The Manufacturing Associates will be involved in the Downstream and central services manufacturing processing responsibilities. The role may require you to write standard operating procedures and batch records to support plant operations. The ideal candidate must be detail-oriented with troubleshooting abilities. You will be expected to be knowledgeable in General filtration, tangential flow filtration, column chromatography, and aseptic technique. 

Shift: Tuesday-Friday, 6am to 4:30pm  

Work Model: 

Core Lab & Ops: This role typically requires that the majority of the work be conducted on-site and thus will be subject to certain on-site safety protocols during the pandemic.

Responsibilities:

  • Attend daily manufacturing tier 1 meetings and be prepared to communicate current operation status. 
  • Generates / Reviews / Approves new and current SOP’s, batch records, and/or protocols in support of the equipment and manufacturing processes associated with the Downstream and Central Services manufacturing areas. 
  • Supports quality investigations, continuous improvement efforts and engineering activities as they directly impact the functionality of the manufacturing areas. 
  • Ensure maintenance, upkeep, and organization, of the facility and processes within the Downstream and central services manufacturing areas. 
  • Demonstrated ability to work with colleagues who represent a diversity of work and conflict resolution styles. 
  • Support the execution of all activities in compliance with environmental health and safety (EHS) requirements, and good manufacturing procedures (cGMPs) 

Requirements:

  • High school degree to BS in any field. Enrollment in a Biotech Certificate Program. 
  • Preferably 1-2 years of professional experience in a regulated industry. Experience with downstream and/or solution prep is not required but experience is preferred. 
  • Ability to accurately perform arithmetic calculations including fractions, decimals, percentages and basic algebra.  
  • Ability to read, understand, and follow procedures. Be computer proficient, especially in Microsoft Office (Word, Outlook, Excel). 
  • Ability and desire to work in a fast-paced, start-up environment is essential  
  • Strong collaboration, teamwork and communication skills  
  • Detail-oriented and independently motivated is a must. 
  • General knowledge of and adherence to cGMPs. 

General Manufacturing: Drug Substance/Central Svcs: 

  • Stand for extended periods of time with periodic stooping / bending / kneeling 
  • Able to lift, push, pull up to 50lbs. 
  • Climb ladders and stairs of various heights. 
  • Work in a controlled environment requiring GxP gowning and wear protective clothing over the head, face, hands, feet, and body. This requires the ability to change clothes into appropriate gowning and personal protective equipment. 
  • Certain tasks may require the use of a respirator; medical clearance will be required in advance. 
  • Must remove all make-up, jewelry, and contact lenses while in the manufacturing environment. 
  • Working in temperature-controlled environments (cold rooms). 

*The pay range for this position is $23 - $28/hour.

#LI-AJ1 #Onsite

The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location.


This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment.

Pay Range
$23—$28 USD
 
Full Time employees across the globe enjoy a range of benefits, including, but not limited to:
 
·         Generous vacation time and public holidays observed by the company
·         Volunteer days
·         Long term incentive and Employee stock purchase plans or equivalent offerings
·         Employee wellbeing benefits
·         Fitness reimbursement
·         Tuition sponsoring
·         Professional development plans
 
* Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.

See our Privacy Policy.
 
Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation.  Inquiries on developing a recruiting relationship with us, may be directed to: talentacquisition@ultragenyx.com.
Key Skills
ManufacturingDownstream processingCentral servicesGene therapyGMPFiltrationTangential flow filtrationColumn chromatographyAseptic techniqueSOP writingBatch recordsTroubleshootingQuality investigationsEHS complianceMicrosoft Office
Categories
ManufacturingScience & ResearchHealthcareEngineering
Benefits
Generous vacation timePublic holidaysVolunteer daysLong term incentive plansEmployee stock purchase plansEmployee wellbeing benefitsFitness reimbursementTuition sponsoringProfessional development plans